Genome regulation is all non-local

maps and functions

Rao

pp. 489-511

in: Shyam Wuppuluri, Francisco A. Doria (eds), The map and the territory, Berlin, Springer, 2018

Abstrakt

In this chapter, we try to envision genomes both as macroscopic entities that living systems carry in the form of genetic information as well as relevant nitty-gritty details of the mechanisms that help maintain genome stability. The human genome contains approximately 6 billion bases of DNA, extending approximately to 2 m of DNA in a cell.